American medical botany : being a collection of the native medicinal plants of the United States, 1817 (pdf)
"American Medical Botany was intended for the public and offered descriptions of each depicted plant’s botanical history, chemical analysis, and medical uses. It was the only book published in the United States prior to the introduction of chromolithography to have its plates mechanically printed in color. Bigelow initially planned to use hand colored copperplate engravings but, when this proved be too ambitious, turned to aquatint plates printed in colors à la poupée, with some finished by hand."
Digitized by the Historical Medical Library of The College of Physicians of Philadelphia