Aspidosperma quebracho (Aspidosperma quebracho-blanco) - Quebracho Blanco
"CONSTITUENTS: The bark of Quebracho contains at least six alkaloids. Aspidospermine, which is thought to be one of these, is not a single alkaloid, but represents the full activity of the drug; dose, ¼ to ½ grain.
PREPARATIONS: Fluid Extract Quebracho, not miscible with water; dose: fifteen minims to one fluid drachm. Solid Extract Quebracho; one part equals ten of drug; dose: one to three grains.
Therapy: Hale calls it the digitalis of the lungs and lauds it for its influence on difficult breathing without much distinction as to the cause.
The agent has quite a positive influence in malarial fevers.
In thrombosis of the pulmonary artery, in some eases of apoplexy, and in uremic dyspnea, it has been of great service. Those of our own physicians who have used it wherever there is difficulty in breathing, are enthusiastic in praise of the relief it gives. It overcomes some severe cases of cyanosis, and although its influence is not always permanent, it often prolongs life and the relief is most grateful to the patient.
It undoubtedly removes temporary obstruction to the oxidation of the blood and by stimulating the respiratory centers it increases oxidation. and facilitates the excretion of carbonic acid.
The agent has quite a positive influence in malarial fevers with or without lung complications, acting as a sedative, antiperiodic and febrifuge. It is not widely used for this purpose and it does not influence other fevers."
(Finley Ellingwood: The American Materia Medica, Therapeutics and Pharmacognosy, 1915)