Croton tiglium - Croton Oil
"CONSTITUENTS: Glucosides of tiglinic, formic, isobutyric and other acids. The vesicating principle is soluble in alcohol, while the purgative principle is insoluble.
The dose of the oil is from one to two minims, best administered in emulsion or pill form. It is not to be administered if there is gastric or intestinal irritation or inflammation, or if there is great weakness or prostration.
A single drop is usually a sufficient dose. This may be administered disguised in anything the patient can be made to take. Dropped on the tongue it acts quickly. Two drops will produce violent action in most cases."
(Finley Ellingwood: The American Materia Medica, Therapeutics and Pharmacognosy, 1915)