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"[Plin. Nat. 20.62.] - CUNILA GALLINACEA, OR ORIGANUM: FIVE REMEDIES.
There is another variety, again, known to our people as “cunila gallinacea,” and to the Greeks as Heracleotic origanum. Beaten up with salt, this plant is good for the eyes; and it is a remedy for cough and affections of the liver. Mixed with meal, and taken as a broth, with oil and vinegar, it is good for pains in the side, and the stings of serpents in particular.”

"[Plin. Nat. 20.69.] - THREE VARIETIES OF HERACLEOTIC ORIGANUM: THIRTY REMEDIES.
Heraclium, again, comprehends three varieties; the first, which is the darkest, has broader leaves than the others, and is of a glutinous nature; the second, which has leaves of a more slender form, and not unlike sampsuchum in appearance, is by some persons called “prasion,” in preference: the third is of an intermediate nature between the other two, but is less efficacious for medicinal purposes than either. But the best kind of all is that of Crete, for it has a particularly agreeable smell; the next best being that of Smyrna, which has even a more powerful odour than the last. The Heracleotic origanum, however, known by the name of “onitis,” is the one that is the most esteemed for taking in drink.
Origanum, in general, is employed for repelling serpents; and it is given boiled to persons suffering from wounds. Taken in drink, it is diuretic; and mixed with root of panax, it is given for the cure of ruptures and convulsions. In combination with figs or hyssop, it is prescribed for dropsical patients in doses of one acetabulum, being reduced by boiling to one sixth. It is good also for the itch, prurigo, and leprosy, taken just before the bath. The juice of it is injected into the ears with milk; it being a cure, also, for affections of the tonsils and the uvula, and for ulcers of the head. A decoction of it, taken with the ashes in wine, neutralizes poison by opium or gypsum. Taken in doses of one acetabulum, it relaxes the bowels. It is applied as a liniment for bruises and for tooth-ache; and mixed with honey and nitre, it imparts whiteness to the teeth. It has the effect, also, of stopping bleeding at the nose.
A decoction of this plant, with barley-meal, is employed for imposthumes of the parotid glands; and, beaten up with nut-galls and honey, it is used for roughness of the trachea: the leaves of it, with honey and salt, are good, too, for the spleen. Boiled with vinegar and salt, and taken in small doses, it attenuates the phlegm, when very thick and black; and beaten up with oil, it is injected into the nostrils for jaundice. When persons are affected with lassitude, the body is well rubbed with it, care being taken not to touch the abdomen. Used with pitch, it is a cure for epinyctis, and, applied with a roasted fig, it brings boils to a head. Employed with oil and vinegar, and barley-meal, it is good for scrofulous swellings; and applied topically in a fig, it is a cure for pains in the sides. Beaten up, and applied with vinegar, it is employed as a liniment for bloody fluxes of the generative organs, and it accelerates the lochial discharge after child-birth.”
(The Natural History. Pliny the Elder. John Bostock, M.D., F.R.S. H.T. Riley, Esq., B.A. London. Taylor and Francis, Red Lion Court, Fleet Street. 1855.)